Search results for "effect [strong interaction]"

showing 10 items of 170 documents

The substituent effect of π-electron delocalization in N-methylamino-nitropyridine derivatives: crystal structure and DFT calculations

2020

AbstractThe crystal and molecular structures of 3-(N-methylamino)-2-nitropyridine, 5-(N-methylamino)-2-nitropyridine and 2-(N-methylamino)-5-nitropyridine have been characterized by X-ray diffraction. To perform conformational analysis, the geometries of the compounds as well as their conformers and rotamers were optimized at the B3LYP/6-311++G(3df,3pd) level. The resulting data were used to analyze the π-electron delocalization effect in relation to the methylamino group rotation in ortho-, meta- and para-substitution positions. Quantitative aromaticity indices were calculated based on which we estimated the electronic structures of the analyzed compounds. The substituent effect of the met…

010405 organic chemistryAromaticityCrystal structureSubstituentAromaticityCrystal structure010402 general chemistryCondensed Matter PhysicsRing (chemistry)DFT calculations01 natural sciences0104 chemical sciencesCrystallographychemistry.chemical_compoundDelocalized electronSubstituent effectchemistryCharge of the substituent active regionIntramolecular forcePyridineSubstituent effect stabilization energyPhysical and Theoretical ChemistryConformational isomerismStructural Chemistry
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Distribution of sea urchins living near shallow water CO2 vents is dependent upon species acid-base and ion-regulatory abilities.

2013

To reduce the negative effect of climate change on Biodiversity, the use of geological CO2 sequestration has been proposed; however leakage from underwater storages may represent a risk to marine life. As extracellular homeostasis is important in determining species' ability to cope with elevated CO2, we investigated the acid-base and ion regulatory responses, as well as the density, of sea urchins living around CO2 vents at Vulcano, Italy. We conducted in situ transplantation and field-based laboratory exposures to different pCO2/pH regimes. Our results confirm that sea urchins have some ability to regulate their extracellular fluid under elevated pCO2. Furthermore, we show that even in cl…

0106 biological sciencesSettore BIO/07 - EcologiaGeological Phenomena010504 meteorology & atmospheric sciencesClimate ChangeSpecies distributionBiodiversityMarine lifeAquatic ScienceOceanography01 natural sciencesParacentrotus lividushowever leakage from underwater storages may represent a risk to marine life. As extracellular homeostasis is important in determining species' ability to cope with elevated CO2 we investigated the acid-base and ion regulatory responses as well as the density of sea urchins living around CO2 vents at Vulcano Italy. We conducted in situ transplantation and field-based laboratory exposures to different pCO2/pH regimes. Our results confirm that sea urchins have some ability to regulate their extracellular fluid under elevated pCO2. Furthermore we show that even in closely-related taxa divergent physiological capabilities underlie differences in taxa distribution around the CO2 vent. It is concluded that species distribution under the sort of elevated CO2 conditions occurring with leakages from geological storages and future ocean acidification scenarios may partly be determined by quite subtle physiological differentiation.Mediterranean seaBenthosAnimalsSeawater14. Life underwaterEcosystem0105 earth and related environmental sciencesbiologyEcology010604 marine biology & hydrobiologyTo reduce the negative effect of climate change on Biodiversity the use of geological CO2 sequestration has been proposedOcean acidificationCarbon DioxideHydrogen-Ion Concentrationbiology.organism_classificationAdaptation PhysiologicalPollutionTransplantationOceanographyItaly13. Climate actionSea UrchinsWater Pollutants Chemical
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Shift in Tuna Catches due to Ocean Warming.

2017

Ocean warming is already affecting global fisheries with an increasing dominance of catches of warmer water species at higher latitudes and lower catches of tropical and subtropical species in the tropics. Tuna distributions are highly conditioned by sea temperature, for this reason and their worldwide distribution, their populations may be a good indicator of the effect of climate change on global fisheries. This study shows the shift of tuna catches in subtropical latitudes on a global scale. From 1965 to 2011, the percentage of tropical tuna in longliner catches exhibited a significantly increasing trend in a study area that included subtropical regions of the Atlantic and western Pacifi…

0106 biological sciencesTime Factors010504 meteorology & atmospheric sciencesEffects of global warming on oceanslcsh:MedicineMarine and Aquatic SciencesOceanographyGlobal Warming01 natural sciencesOceansTropical climateClimate changeZoologíaPesqueríaslcsh:ScienceIndian OceanNorthern HemisphereLatitudeMultidisciplinaryGeographyFishesTemperatureAgricultureOsteichthyesVertebratesResearch ArticleCartographyOceans and SeasFisheriesClimate changeSede Central IEOSubtropicsAnimalsVulnerability of tropical countries to climate change14. Life underwaterOcean TemperatureTropical tuna distribution0105 earth and related environmental sciencesTropical ClimatePacific OceanTuna010604 marine biology & hydrobiologylcsh:RGlobal warmingOrganismsBiology and Life SciencesTropicsNumerical Analysis Computer-AssistedBodies of WaterModels TheoreticalFisherySea surface temperatureEffect on fisheries13. Climate actionEarth SciencesEnvironmental sciencelcsh:QTunaGeographic areas
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Bevacizumab diminishes inflammation in an acute endotoxin-induced uveitis model

2017

Este artículo se encuentra disponible en la página web de la revista en la siguiente URL: https://www.frontiersin.org/articles/10.3389/fphar.2018.00649/full Introduction: Uveitis is an eye disease characterized by inflammation of the uvea and an early and exhaustive diagnosis is essential for its treatment. The aim of our study is to assess the potential toxicity and anti-inflammatory efficacy of Bevacizumab in an experimental uveitis model by subcutaneously injecting lipopolysaccharide into Lewis rats and to clarify its mechanism. Material and Methods: Blood–aqueous barrier integrity was assessed 24 h after endotoxin-induced uveitis (EIU) by analyzing two parameters: cell count and protein…

0301 basic medicineChemokineLipopolysaccharidegenetic structuresmedicine.medical_treatmentÚvea - Efectos de los medicamentos.chemokinesPharmacologymedicine.disease_causeendotoxin-induced uveitischemistry.chemical_compound0302 clinical medicineMedicineoxidative stressPharmacology (medical)Bevacizumab - Efectos fisiológicos.Bevacizumab - Efectos secundarios.Uvea - Effect of drugs on.Original ResearchEstrés oxidativo.biologyOxidative stress.medicine.anatomical_structureCytokineToxicityOjos - Enfermedades - Tratamiento.medicine.symptomUveitisPharmacology.InflammationFarmacología.bevacizumabBevacizumab - Physiological effect.Bevacizumab - Side effects.03 medical and health sciencesUveitis - Treatment.Eyes - Diseases - Treatment.Pharmacologybusiness.industrylcsh:RM1-950Uveítis - Tratamiento.Uveamedicine.diseaseeye diseasescytokines030104 developmental biologylcsh:Therapeutics. Pharmacologychemistryinflammation030221 ophthalmology & optometrybiology.proteinsense organsbusinessOxidative stress
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Effect of nutritional supplementations on physical performance and muscle strength parameters in older people: A systematic review and meta-analysis

2019

Malnutrition plays a role in the development of poor physical performance, frailty and sarcopenia. The use of nutritional supplementations for improving physical performance and muscle strength parameters in older people is unclear. We therefore aimed to summarize the effect of nutritional supplementations compared to placebo on physical performance (i.e. tests more investigating physical function, utilising aerobic capacity & muscle power) and muscle strength (i.e. tests depending on muscle power) outcomes in older people in randomized controlled trials (RCTs). A literature search in major databases was undertaken until the 01st September 2018. Eligible studies were RCTs investigating …

0301 basic medicineMalemedicine.medical_specialtyAgingSarcopeniaNutritional SupplementationPlaceboBiochemistrylaw.inventionPhysical performance03 medical and health sciencesA systematic review and meta-analysis.- Ageing research reviews cilt.51 ss.48-54 2019 [VERONESE N. STUBBS B. PUNZI L. Soysal P. INCALZI R. SALLER A. MAGGI S. -Effect of nutritional supplementations on physical performance and muscle strength parameters in older people]0302 clinical medicineRandomized controlled triallawmedicineHumansMolecular BiologyAgedRandomized Controlled Trials as TopicNutritionAged 80 and overHand Strengthbusiness.industryMuscle strengthPhysical Functional Performancemedicine.diseaseConfidence intervalMalnutritionMeta-analysis030104 developmental biologyTreatment OutcomeNeurologyPhysical performanceSarcopeniaMeta-analysisDietary SupplementsPhysical therapyFemalebusiness030217 neurology & neurosurgeryBiotechnology
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Mapping brain activity with flexible graphene micro-transistors

2016

arXiv:1611.05693v1.-- et al.

0301 basic medicineMaterials scienceFOS: Physical sciences02 engineering and technologylaw.invention03 medical and health scienceslawGeneral Materials ScienceElectronicsPhysics - Biological PhysicsNeural implantsBioelectronicsBioelectronicsbusiness.industryGrapheneSensorsMechanical EngineeringTransistorGeneral Chemistry021001 nanoscience & nanotechnologyCondensed Matter PhysicsField-effect transistorsMicroelectrodeBrain implant030104 developmental biologyBiological Physics (physics.bio-ph)Mechanics of MaterialsFOS: Biological sciencesQuantitative Biology - Neurons and CognitionOptoelectronicsNeurons and Cognition (q-bio.NC)Charge carrierField-effect transistorGraphene0210 nano-technologybusiness2D Materials
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High Fruit and Vegetable Consumption and Moderate Fat Intake Are Associated with Higher Carotenoid Concentration in Human Plasma

2021

This research was funded by CICYT [AGL2016-75329-R] and CIBEROBN from the Instituto de Salud Carlos III, ISCIII from the Ministerio de Ciencia, Innovación y Universidades, (AEI/FEDER, UE), Generalitat de Catalunya (GC) [2017SGR196]. The PREDIMED-Plus trial was supported by the official Spanish Institutions for funding scientific biomedical research, CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn) and Instituto de Salud Carlos III (ISCIII), through the Fondo de Investigación para la Salud (FIS), which is co-funded by the European Regional Development Fund (four coordinated Fondo de Investigaciones Sanitarias projects lead by J.S.-S. and J.V., including the following projects: PI13…

0301 basic medicineMediterranean dietFruit (Feed)PhysiologyClinical BiochemistryCarotenoidesLiquid chromatography030209 endocrinology & metabolismmatrix effect absorptionBiochemistryArticle03 medical and health sciences0302 clinical medicineMediterranean cookingFat intakeplasma carotenoidsMediterranean dietCuina mediterràniapolycyclic compoundsliquid chromatographyFood scienceCuina (Hortalisses)Molecular BiologyCarotenoidmass spectrometry2. Zero hungerchemistry.chemical_classificationConsumption (economics)030109 nutrition & dieteticsbioactive compoundsMass spectrometryorganic chemicalslcsh:RM1-950food and beveragesPREDIMED-Plus studyCell Biologydietary fatsphytochemicalsCarotenoidsbiological factorsCooking (Vegetables)3. Good healthlcsh:Therapeutics. PharmacologychemistryFruita (Aliment)Human plasmasense organsMatrix effect absorptionAntioxidants
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Trichomonicidal and parasite membrane damaging activity of bidesmosic saponins from Manilkara rufula.

2017

The infection caused by Trichomonas vaginalis is the most common but overlooked non-viral sexually transmitted disease worldwide. Treatment relies on one class of drugs, the 5-nitroimidazoles, but resistance is widespread. New drugs are urgently needed. We reported the effect of crude and purified saponin fractions of Manilkara rufula against Trichomonas vaginalis. The compound responsible for antitrichomonal activity was isolated and identified as an uncommon bidesmosic saponin, Mi-saponin C. This saponin eliminated parasite viability without toxicity against the human vaginal epithelial line (HMVII). In addition, the isolated saponin fraction improved the metronidazole effect against a me…

0301 basic medicineSexually transmitted diseaseNeutrophilsCell MembranesSaponinlcsh:Medicinemedicine.disease_causePathology and Laboratory MedicineBiochemistryMass SpectrometryAnalytical ChemistryWhite Blood CellsOxidative DamageSpectrum Analysis TechniquesAnimal CellsMedicine and Health SciencesParasite hostingElectron Microscopylcsh:Sciencechemistry.chemical_classificationSexually transmitted diseasesTrichomonas VaginalisMicroscopyMultidisciplinaryEukaryotaProtistsMatrix-Assisted Laser Desorption Ionization Mass Spectrometrymusculoskeletal systemChemistryFlagellaToxicityPhysical SciencesVaginaTrichomonasFemaleCellular TypesCellular Structures and OrganellesPathogensMalalties de transmissió sexualIntracellularmedicine.drugResearch ArticlePathogen MotilityEfecte dels medicaments sobre els microorganismesVirulence FactorsImmune CellsImmunologyBiologyResearch and Analysis Methodscomplex mixturesMicrobiologyCell Line03 medical and health sciencesParasite Groupsparasitic diseasesmedicineTrichomonas vaginalisSaponinasHumansTrophozoitesResistència als medicamentsManilkaraBlood CellsCell Membranelcsh:ROrganismsBiology and Life SciencesCell BiologyIntracellular MembranesSaponinsbiology.organism_classificationCell membranescarbohydrates (lipids)MetronidazoleMicroscopy Electron030104 developmental biologychemistryManilkara rufulaDrug resistanceEffect of drugs on microorganismsTrichomonas vaginalisParasitologyTransmission Electron Microscopylcsh:QReactive Oxygen SpeciesApicomplexaMembranes cel·lularsChromatography LiquidPRODUTOS NATURAISPLoS ONE
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Visual mismatch negativity (vMMN): A review and meta-analysis of studies in psychiatric and neurological disorders

2016

The visual mismatch negativity (vMMN) response is an event-related potential (ERP) component, which is automatically elicited by events that violate predictions based on prior events. VMMN experiments use visual stimulus repetition to induce predictions, and vMMN is obtained by subtracting the response to rare unpredicted stimuli from those to frequent stimuli. One increasingly popular interpretation of the mismatch response postulates that vMMN, similar to its auditory counterpart (aMMN), represents a prediction error response generated by cortical mechanisms forming probabilistic representations of sensory signals. Here we discuss the physiological and theoretical basis of vMMN and review…

2805 Cognitive Neurosciencespecific adaptation (SSA)skitsofrenia3205 Experimental and Cognitive Psychologyeffect sizerepetition suppression (RS)610 Medicine & healthStimulusRepetition suppression (RS)stimulus specific adaptation (SSA)170 Ethics3206 Neuropsychology and Physiological Psychologyschizophreniavisual mismatch negativity (vMMN)10237 Institute of Biomedical EngineeringVisual mismatch negativity (vMMN)
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Public policy in families and successions regulations : the case of ?talaq?

2021

According to EU Regulations on transnational families and successions, a foreign rule remains without effect if it is deemed contrary to the so-called public policy (ordre public) of the forum?s legal system. As a consequence, judges have to evaluate whether the application of foreign law is incompatible with fundamental principles of the domestic law, especially whether it would constitute a violation against human rights. An outstanding controversial issue is today represented by Islamic repudiation (talaq): two contrasting Italian judicial decisions of August 2020 may illustrate how difficult it could be to determine what public policy is.

:CIENCIAS JURÍDICAS [UNESCO]Marco According to EU Regulations on transnational families and successionsjudges have to evaluate whether the application of foreign law is incompatible with fundamental principles of the domestic law2386-4567 22661 Actualidad jurídica iberoamericana 587897 2021 15 8113559 Public policy in families and successions regulations the case of ?talaq? Rizzutimigrationhuman rightsa foreign rule remains without effect if it is deemed contrary to the so-called public policy (ordre public) of the forum?s legal system. As a consequenceespecially whether it would constitute a violation against human rights. An outstanding controversial issue is today represented by Islamic repudiation (talaq): two contrasting Italian judicial decisions of August 2020 may illustrate how difficult it could be to determine what public policy is. Public policymigracióntalaq. 221 241Orden públicoUNESCO::CIENCIAS JURÍDICAStwo contrasting Italian judicial decisions of August 2020 may illustrate how difficult it could be to determine what public policy is. Public policy [especially whether it would constitute a violation against human rights. An outstanding controversial issue is today represented by Islamic repudiation (talaq)]talaq.derechos humanos
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